Chondroprotective effect of melatonin and strontium ranelate in animal model of osteoarthritis
Purpose: To analyze the action of strontium ranelate (SR) and melatonin in isolation or in association in knees, liver and kidneys of CREAM rats Wistar with induced osteoarthritis (OA).Methods: Thirty male rats were induced to OA through an anterior cruciate ligament transection (ACLT), and treated with melatonin and SR in isolation or in associati